| Player | # | Pos | Ht | Wt | Age | College |
|---|---|---|---|---|---|---|
| *Alex Anzalone | #47 | LB | 6′ 3″ | 241 | 23 | Florida |
| Terron Armistead | #72 | LT | 6′ 5″ | 304 | 26 | Arkansas-Pine Bluff |
| Chris Banjo | #37 | S | 5′ 10″ | 204 | 27 | SMU |
| Vonn Bell | #48 | SS | 5′ 11″ | 205 | 23 | Ohio State |
| *Adam Bighill | #99 | LB | 5′ 10″ | 230 | 29 | Central Washington |
| Drew Brees+ | #9 | QB | 6′ 0″ | 209 | 38 | Purdue |
| Raphael Bush | #25 | FS | 5′ 11 | 203 | 30 | South Carolina State |
| *Austin Carr | #80 | WR | 6′ 1″ | 195 | 24 | Northwestern |
| Brandin Coleman | #16 | WR | 6′ 6″ | 225 | 25 | Rutgers |
| Ken Crawley | #46 | LCB | 6′ 1″ | 180 | 24 | Colorado |
| Chase Daniel | #10 | QB | 6′ 0″ | 225 | 31 | Missouri |
| Tyeler Davison | #95 | RDT | 6′ 2″ | 315 | 25 | Fresno State |
| *Trey Edmunds | #33 | RB | 6′ 2″ | 223 | 23 | Maryland |
| Coby Fleener | #82 | TE | 6′ 6″ | 251 | 29 | Stanford |
| Jonathan Freeny | #55 | DE | 6′ 2″ | 245 | 28 | Rutgers |
| John Fullerton | #77 | OT | 6′ 5″ | 300 | 26 | Washington State |
| Ted Ginn | #19 | WR | 5′ 11″ | 180 | 32 | Ohio State |
| *Garrett Griffin | #45 | TE | 6′ 4″ | 240 | 23 | Air Force |
| *Justin Hardee | #34 | DB | 6′ 1″ | 200 | 23 | Illinois |
| Bryce Harris | #79 | OT | 6′ 6″ | 300 | 28 | Fresno State |
| De’Vante Harris | #21 | CB | 5′ 11″ | 190 | 24 | Texas A&M |
| *Trey Hickerson | #91 | DE | 6′ 4″ | 270 | 23 | Florida Atlantic |
| Josh Hill | #89 | TE | 6′ 5″ | 229 | 27 | Idaho St |
| *Taysom Hill | #7 | QB/WR/RB | 6′ 2″ | 221 | 27 | BYU |
| Gerald Hodges | #50 | LB | 6′ 2″ | 236 | 26 | Penn State |
| Michael Hoomanawanui | #84 | TE | 6′ 4″ | 265 | 29 | Illinois |
| John Hughes | #92 | DT | 6′ 2″ | 320 | 29 | Cincinnati |
| Mark Ingram+ | #28 | RB | 5′ 9″ | 215 | 28 | Alabama |
| George Johnson | #90 | DE | 6′ 4″ | 265 | 30 | Rutgers |
| Cameron Jordan+★ | #94 | LDE | 6′ 4″ | 287 | 28 | California |
| *Alvin Kamara+ | #41 | RB | 5′ 9″ | 215 | 22 | Tennessee |
| Senio Kelemete | #65 | LG | 6” 3″ | 307 | 27 | Washington |
| Hau’oli Kikaha | #44 | LB | 6′ 3″ | 246 | 25 | Washington |
| A.J. Klein | #53 | RLB | 6′ 1″ | 240 | 26 | Iowa State |
| John Kuhn | #29 | FB | 6′ 0″ | 255 | 35 | Shippensburg |
| Daniel Lasco | #36 | RB | 6′ 1″ | 205 | 25 | California |
| *Marshon Lattimore+ | #23 | RCB | 6′ 0″ | 192 | 21 | Ohio State |
| Josh LeRibeus | #61 | OG | 6′ 2″ | 315 | 28 | SMU |
| Tommy Lee Lewis | #87 | WR/KR | 5′ 7″ | 168 | 25 | Northern Illinois |
| Zach Line | #42 | FB | 6′ 1″ | 233 | 27 | SMU |
| *Mitchell Lowen | #70 | DE | 6′ 5″ | 275 | 24 | Arkansas |
| Will Lutz | #3 | K | 5′ 11″ | 184 | 23 | Georgia State |
| *Arthur Maulet | #37 | CB | 6′ 10″ | 190 | 24 | Memphis |
| Micheal Mauti | #56 | LB | 6′ 2″ | 243 | 27 | Penn State |
| Tony McDaniel | #76 | DT | 6″ 7″ | 305 | 32 | Tennessee |
| Dexter McDougle | #30 | CB | 5′ 10″ | 190 | 26 | Maryland |
| Sterling Moore | #24 | CB | 5′ 10″ | 190 | 27 | SMU |
| Thomas Morstead | #6 | P | 6′ 4″ | 225 | 31 | Southern Methodist University |
| *Al-Quadin Muhammad | #97 | DE | 6′ 4″ | 250 | 22 | Miami |
| Alex Okafor | #57 | RDE | 6′ 4″ | 261 | 26 | Texas |
| David Onyemata | #93 | DE | 6′ 4″ | 300 | 25 | Manitoba |
| David Parry | #58 | NT | 6′ 2″ | 317 | 25 | Stanford |
| Andrus Peat | #75 | LG | 6′ 7″ | 312 | 24 | Stanford |
| Adrian Peterson | #28 | RB | 6′ 1″ | 220 | 32 | Oklahoma |
| John Phillips | #86 | TE | 6′ 5″ | 250 | 30 | Virginia |
| *Ryan Ramczyk | #71 | RT | 6′ 6″ | 314 | 23 | Wisconsin |
| Sheldon Rankins | #98 | LDT | 6′ 2″ | 305 | 23 | Louisville |
| Craig Robertson | #52 | LLB | 6′ 1″ | 229 | 28 | North Texas |
| Willie Snead | #83 | WR | 5′ 11″ | 195 | 25 | Ball State |
| Zach Strief | #64 | OT | 6′ 7″ | 320 | 34 | Northwestern |
| Nate Stupar | #54 | OLB | 6′ 2 | 224 | 29 | Penn State |
| Manti Te’o | #51 | MLB | 6′ 1″ | 241 | 26 | Notre Dame |
| Michael Thomas+ | #13 | WR | 6′ 3″ | 212 | 24 | Ohio State |
| Max Unger | #60 | C | 6′ 5″ | 305 | 31 | Oregon |
| Kenny Vaccaro | #32 | SS | 6′ 0″ | 214 | 26 | Texas |
| Larry Warford+ | #67 | RG | 6′ 3″ | 317 | 26 | Kentucky |
| *Marcus Williams | #43 | FS | 6′ 1″ | 195 | 21 | Utah |
| PJ Williams | #26 | LCB | 6′ 0″ | 196 | 24 | Florida State |
| *Zach Wood | #49 | LS | 6′ 3″ | 255 | 24 | SMU |
| *Rookie | ||||||
- * – Rookie
- + – Pro Bowl Selection
- ★- All-Pro Selection