| Player | # | Pos | Ht | Wt | Age | College |
|---|---|---|---|---|---|---|
| Isa Addul-Quddus | #42 | S | 6′ 1" | 220 | 23 | Fordham |
| Adrian Arrington | #87 | WR | 6′ 3" | 192 | 27 | Michigan |
| Drew Brees | #9 | QB | 6′ 0″ | 209 | 33 | Purdue |
| *Charles Broughton | #72 | DE | 6′ 6" | 272 | 25 | TCU |
| Charles Brown | #71 | T | 6′ 5″ | 284 | 25 | USC |
| Brodrick Bunkley | #77 | DT | 6′ 2" | 295 | 29 | Florida St |
| Rafeal Bush | #25 | S | 5′ 11" | 197 | 25 | South Carolina St |
| Jermon Bushrod | #74 | T | 6′ 5" | 315 | 28 | Towson |
| *Travis Cadet | #39 | RB | 6′ 1" | 210 | 23 | Appalachian St |
| Jonathan Casillas | #52 | LB | 6′ 1" | 227 | 25 | Wisconsin |
| Chris Chamberlain | #56 | LB | 6′ 2" | 226 | 27 | Tulsa |
| Jed Collins | #45 | FB | 6′ 1" | 255 | 26 | Washington St |
| Marques Colston | #12 | WR | 6′ 4" | 225 | 29 | Hofstra | Chase Daniel | #10 | QB | 6′ 0 " | 225 | 26 | Missouri |
| Brian De La Puente | #60 | C | 6′ 3" | 306 | 27 | California |
| Justin Dresher | #47 | LS | 6′ 1" | 230 | 25 | Colorado |
| Sedrick Ellis | #98 | DT | 6′ 1" | 307 | 27 | USC |
| Jahri Evans | #73 | G | 6′ 4" | 318 | 29 | Bloomberg |
| Jarred Fayson | #86 | WR | 6′ 0" | 213 | 25 | Illinois |
| Junior Galette | #93 | DE | 6′ 2" | 258 | 24 | Stillman |
| Chris Givens | #17 | WR | 6′ 2" | 203 | 24 | Miami (Ohio) |
| Jimmy Graham | #80 | TE | 6′ 6" | 260 | 26 | Miami(Fla) |
| Jabri Greer | #33 | CB | 5′ 11" | 180 | 30 | Tennessee |
| Ben Grubbs | #66 | OG | 6′ 3″ | 311 | 28 | Auburn |
| *Salim Hakim | #18 | WR | 5′ 11" | 188 | 22 | Palomar J.C. |
| Roman Harper | #41 | SS | 6′ 1″ | 200 | 30 | Alabama |
| *Bryce Harris | #79 | T | 6′ 6" | 330 | 24 | Fresno St |
| Garrett Hartely | #5 | K | 5′ 8" | 208 | 26 | Oklahoma |
| David Hawthorne | #57 | LB | 6′ 0" | 230 | 27 | TCU |
| Devery Henderson | #19 | WR | 5′ 11" | 200 | 29 | LSU |
| Rick Henry | #65 | G | 6′ 4" | 310 | 25 | Nebraska |
| Will Herring | #53 | LB | 6′ 3" | 215 | 29 | Auburn |
| *Akiem Hicks | #76 | DT | 6′ 5" | 318 | 23 | Regina |
| Micheal Higgins | #81 | TE | 6′ 5" | 242 | 25 | Nebrasaka-Omaha |
| Ramon Humbar | #54 | LB | 5′ 11″ | 232 | 25 | North Dakato St. |
| Mark Ingram | #28 | RB | 5′ 9" | 215 | 23 | Alabama |
| Chris Ivory | #29 | RB | 6′ 0" | 222 | 24 | Washington St, Tiffin |
| Malcolm Jenkins | #27 | CB | 6′ 0" | 204 | 25 | Ohio St. |
| *Austin Johnson | #96 | LB | 6′ 2" | 240 | 23 | Tennessee |
| Tom Johnson | #72 | DT | 6′ 3″ | 288 | 28 | Southern Mississippi |
| Cameron Jordan | #94 | DE | 6′ 3" | 287 | 23 | California |
| *Ryan Lee | #63 | G | 6′ 3" | 308 | 24 | Furman |
| Curtis Lofton | #50 | LB | 6′ 2" | 238 | 26 | Okiahoma |
| Elbert Mack | #44 | CB | 5" 10" | 175 | 26 | Troy |
| Turk McBride | #90 | DE | 6′ 4" | 285 | 27 | Tennessesse |
| Joe Morgan | #13 | WR | 6′ 1" | 184 | 24 | Walsh |
| Lance Moore | #16 | WR | 5′ 9" | 190 | 29 | Toledo |
| Thomas Morstead | #6 | P | 6′ 4" | 225 | 26 | Southren Methodist |
| Jericho Nelson | #37 | G | 5′ 10″ | 216 | 23 | Arkansas |
| Eric Olsen | #69 | G | 6′ 3" | 301 | 24 | Notre Dame |
| Preston Parker | #87 | WR | 6′ 0" | 200 | 25 | North Alabama |
| Johnny Patrick | #32 | CB | 5′ 11" | 191 | 24 | Louisville |
| Jay Richardson | #99 | DE | 6′ 5" | 280 | 28 | Ohio St |
| Patrick Robinson | #34 | CB | 5′ 11" | 191 | 24 | Florida St. |
| Will Robinson | #68 | T | 6′ 5" | 297 | 28 | San Deigo St |
| Courtney Roby | #15 | WR | 6′ 0″ | 189 | 30 | Indiana |
| Greg Romeus | #79 | DE | 6′ 5" | 267 | 24 | Pittsburgh |
| Scott Shanle | #58 | LB | 6′ 2" | 245 | 33 | Nebraska |
| Will Smith | #91 | DE | 6′ 3″ | 282 | 31 | Ohio St. |
| Darren Sproles | #43 | RB | 5′ 6" | 181 | 29 | Kanas St. |
| *Ryan Steed | #30 | CB | 5′ 11" | 185 | 22 | Furman |
| Zach Strief | #64 | T | 6′ 7″ | 320 | 29 | Northwestern |
| Andy Tanner | #14 | WR | 6′ 0" | 183 | 24 | Midwestern St |
| Pierre Thomas | #23 | RB | 5′ 11" | 215 | 28 | Illinois |
| David Thomas | #85 | TE | 6′ 3″ | 248 | 29 | Texas |
| *Andy Tiller | #67 | G | 6′ 5″ | 326 | 23 | Syracuse |
| *Nick Toon | #88 | WR | 6′ 4" | 218 | 24 | Wisconsin |
| *Dion Turner | #31 | CB | 5′ 11" | 194 | 23 | Southern Utah |
| Johnathon Vilma | #51 | MLB | 6′ 1" | 230 | 30 | Miami (Fla) |
| *Tyrunn Walker | #75 | DT | 6′ 3" | 294 | 22 | Tulsa |
| *Corey White | #24 | CB | 6′ 1" | 205 | 22 | Samford |
| Martez Wilson | #95 | LB | 6′ 4″ | 250 | 23 | East Illinois |
| *Rookie | ||||||
