| Rank | Player | Catches | Years |
|---|---|---|---|
| 1 | Marques Colston☨ | 711 | 2006-2015 |
| 2 | Eric Martin☨ | 532 | 1985-1993 |
| 3 | Joe Horn☨ | 523 | 2000-2006 |
| 4 | Michael Thomas | 510 | 2016-2020 |
| 5 | Jimmy Graham | 386 | 2010-2014 |
| 6 | Lance Moore☨ | 346 | 2005-2013 |
| 7 | Pierre Thomas☨ | 327 | 2007-2014 |
| 8 | Danny Abramowicz☨ | 309 | 1967-1973 |
| 9 | Reggie Bush☨ | 294 | 2006-2010 |
| 10 | Tony Galbreath☨ | 284 | 1976-1980 |
| 11 | Quinn Early | 270 | 1991-1995 |
| 12 | Hoby Brenner☨ | 267 | 1981-1993 |
| 13 | Dalton Hilliard☨ | 249 | 1986-1993 |
| 14 | Devery Henderson☨ | 245 | 2004-2012 |
| 15 | Deuce McAllister☨ | 234 | 2001-2008 |
| 16 | Darren Sproles | 232 | 2011-2013 |
| 17 | Mark Ingram | 228 | 2011-2018 |
| 18 | Brandin Cooks | 215 | 2014-2016 |
| 19 | Henry Childs☨ | 207 | 1974-1980 |
| 20 | Donte Stallworth | 195 | 2002-2005 |
- Bold Text – Currently Still Active on Team
- ☨ – Member of New Orleans Saints Hall of Fame
